Bespoke illustration created for the cover of the journal Advanced Healthcare Materials of December 2015
KNOCKING DOWN COLLAGEN SYNTHESIS IN LIVER FIBROSIS
Nanomedicine: In Vivo Gene-Silencing in Fibrotic Liver by siRNA-Loaded Cationic Nanohydrogel Particles (Adv. Healthcare Mater. 18/2015)
On page 2809, D. Schuppan, R. Zentel, and co-workers show how systemically administered cationic nanohydrogel particles loaded with anti-Col1α1 siRNA target fibrogenic effector cells in the liver and thereby suppress collagen synthesis and attenuate fibrosis.
Progress: Coming soon